GLP-1 dose escalation follows a step-up schedule — this tool turns the published dose ladder for your compound into an actual calendar with real dates, based on your own start date. Need the vial math for each step? Use the GLP-1 Dose Calculator.
Titration schedule builder
A one-off planning tool — nothing here is saved or sent anywhere.
4 weeks per step matches the FDA-labeled schedule for semaglutide and tirzepatide. Any other pace should be set by your prescriber based on tolerability.
How to Use This Planner
Three inputs generate a full calendar schedule instantly.
Pick your compoundLoads that compound's published dose ladder — the same steps used in the GLP-1 Dose Calculator.
Enter your start dateThe date of your first injection at the lowest dose.
Choose your weeks-per-step pace4 weeks matches the FDA-labeled schedule for approved compounds — only change this if your prescriber has specifically set a different pace.
Read your scheduleEvery step's dose and date range, plus a total time to reach the highest listed dose.
Where the Dose Steps and Timing Come From
The dose amounts and default pacing reflect published labeling and trial protocols — this tool just does the date arithmetic.
Semaglutide steps and pace. 0.25mg, 0.5mg, 1mg, 1.7mg, 2.4mg, with a minimum 4-week interval between increases. FDA prescribing information, Ozempic and Wegovy labels.
Tirzepatide steps and pace. 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg, with a minimum 4-week interval between increases. FDA prescribing information, Mounjaro and Zepbound labels.
Retatrutide and cagrilintide steps. Reflect dose levels studied in published Phase 2/3 clinical trials — these compounds are not FDA-approved, and trial protocols continue to evolve. Published Phase 2/3 clinical trial dosing protocols.
Date arithmetic. Each step's end date = start date + (weeks per step × 7) days, chained sequentially through the full dose ladder. Standard calendar arithmetic.
Estimate only — not medical advice. This planner lays out a hypothetical calendar based on published labeled or trial schedules — it does not know your individual tolerability, side effects, or medical history. Actual dose timing, and whether to advance, hold, or reduce a dose at any step, should be directed by your prescriber. Do not use this schedule to self-adjust a prescription.
Frequently Asked Questions
Why does the schedule use 4-week steps by default?
That's the minimum interval specified in the FDA labels for semaglutide and tirzepatide, chosen based on the clinical trials that supported their approval — giving each dose level enough time to assess tolerability before increasing further.
Can I move faster than 4 weeks per step?
Only if directed by your prescriber based on your individual response — the labeled schedule exists specifically to manage side effects like nausea, and accelerating it without medical guidance increases that risk.
What if I need to stay on a dose longer than planned due to side effects?
This tool generates a hypothetical schedule assuming steady progression — real-world titration often pauses at a dose level longer if side effects warrant it. Recalculate with a later start date for the remaining steps if your actual schedule shifts.
Does this tool track whether I've actually taken each dose?
No — this is a planning tool that generates a hypothetical calendar, not a dose log. To track your actual injection history against a plan like this, see the full Peptide Plug app.
Are retatrutide and cagrilintide schedules as reliable as semaglutide and tirzepatide?
No — those two are investigational compounds, and trial dosing protocols can differ from what's shown here or change as research progresses. Semaglutide and tirzepatide schedules reflect final FDA-approved labeling, which is more stable.
What happens after I reach the highest dose in the ladder?
This planner shows the escalation phase only — once you reach the top of the ladder (or whatever maintenance dose your prescriber sets), you'd typically continue at that dose rather than continuing to increase.
Can I use this to plan a de-escalation (dose decrease) instead?
This tool is built for escalating schedules specifically. A dose decrease is a different clinical decision your prescriber would guide directly, not typically following the same step-up ladder in reverse.
Does this tool save my plan anywhere?
No — it's regenerated fresh each time you load the page and nothing is stored. To keep a saved copy, use your browser's print or screenshot function, or track your actual protocol in the full Peptide Plug app.
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