Peptide Plug vs Shotlee
Shotlee is the most complete dedicated HRT tracker of the apps compared on this site — it covers estrogen and progestogen across patch, gel, spray, oral, vaginal, ring, injection and implant, with detailed symptom and bleeding logs. Peptide Plug's HRT coverage is newer and narrower, but it brings cost and vial arithmetic that Shotlee does not describe.
Short version
Shotlee is the stronger fit for menopause and perimenopause HRT specifically — broader route coverage, structured symptom and bleeding tracking, and a free price. Peptide Plug is the stronger fit if you also run peptide or testosterone protocols, need reconstitution and cost math, or want everything on one timeline. Shotlee is free; Peptide Plug is $4.99/mo or $49.99/yr above a one-cycle free tier.
Feature-by-feature
Based on Shotlee's published product and pricing pages and this Peptide Plug build, reviewed September 9, 2026.
| Feature | Peptide Plug | Shotlee |
|---|---|---|
| Platforms | Installable web app for phone, tablet and desktop | Native iOS + Android + web |
| Price | $4.99/mo or $49.99/yr | Free |
| Hormones covered | Estradiol, progesterone, testosterone, hCG, peptides | Estrogen and progestogen/progesterone |
| Routes covered | Patch, gel, spray, oral, injection | Patch, gel, spray, oral, vaginal, ring, injection, implant |
| Symptom tracking | ✓ Informal self-check + free-text notes | ✓ Structured: flushes, sleep, mood, function |
| Bleeding pattern log | Not offered | ✓ Dates, amount, pain, timing |
| Reconstitution math | ✓ Full reconstitution, blend and syringe-unit math | Not stated |
| Cost per dose / run-out | ✓ Cost per dose, per month and vial run-out forecasting | Not stated |
| Supply tracking | ✓ Vials, diluent, reorder and mixed-vial expiry alerts | ✓ Vial amounts, remaining, refill dates |
| Lab tracking | ✓ Manual labs with chart overlays | ✓ Labs when ordered by a clinician |
| Estimated levels | ✓ Estimated level curve + public 86-compound half-life table | ✓ Medication level predictor |
| Also covers TRT / peptides | ✓ Same timeline, one account | Not stated |
| Public calculators | ✓ 17 free calculators, no account | Not stated |
Sources: shotlee.app. "Not stated" means the feature was not described on the pages reviewed.
Where each one wins
Neither is better at everything. These are the honest trade-offs.
Pick Peptide Plug for
- You run more than hormone therapy — peptides, TRT and GLP-1 sit on the same timeline.
- You need reconstitution or syringe-unit math for an injectable.
- You want cost per dose and a run-out date, not just a refill reminder.
- You want free calculators usable with no account and no install.
- You want a published half-life reference covering 86 compounds.
Pick Shotlee for
- It is free, and its HRT coverage is broader than ours today.
- Route coverage includes vaginal products, rings and implants, which we do not model.
- Structured bleeding-pattern tracking, which matters in perimenopause and we do not offer.
- Purpose-built symptom scales for flushes, sleep, mood and daily function.
- Native apps on iOS and Android as well as web.
Which should you pick?
If menopause HRT is the only thing you are tracking, Shotlee is the more complete and cheaper choice and we would rather say so. Peptide Plug earns its place when hormone therapy is one protocol among several, or when vial and cost arithmetic is the hard part.
Common questions
Which is better purely for menopause HRT?
So why would I use Peptide Plug for HRT?
Does Peptide Plug track bleeding patterns?
Does either estimate hormone levels?
Is Shotlee really free?
Try the free tools first
Every Peptide Plug calculator runs in your browser with no account and nothing stored.
Open the free tools