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Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Healing & Recovery

Thymosin Beta-4 — reference

The full 43-amino-acid parent protein that TB-500 is a fragment of; an actin-sequestering protein involved in cell migration and repair.

Regulatory statusNot FDA-Approved
Published half-life~2 hours (animal PK)
Evidence levelLimited data
CategoryHealing & Recovery

Regulatory status

Not FDA-Approved. Not FDA-approved. Has been studied in clinical trials for dry eye and cardiac repair without reaching approval. Banned by WADA.

Reported cautions

⚠ Worth knowing. Much of what is sold as “TB-500” is the fragment rather than this full protein — they are not the same molecule, though they are marketed interchangeably.

Pharmacokinetics

Published figures give an elimination half-life of ~2 hours (animal PK). No robust human plasma half-life study identified.

This figure is tagged Limited data in our evidence system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is Thymosin Beta-4 FDA-approved?
Not FDA-Approved. Not FDA-approved. Has been studied in clinical trials for dry eye and cardiac repair without reaching approval. Banned by WADA.
What is the half-life of Thymosin Beta-4?
Published figures give ~2 hours (animal PK). No robust human plasma half-life study identified.
How reliable is that half-life figure?
It is tagged “Limited data” in our system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only.
What cautions are associated with Thymosin Beta-4?
Much of what is sold as “TB-500” is the fragment rather than this full protein — they are not the same molecule, though they are marketed interchangeably.
Does Peptide Plug publish dosing for Thymosin Beta-4?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell Thymosin Beta-4?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

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Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures