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Peptide Plug is a research and organization tool intended for adults 18 years of age or older. By continuing, you confirm you are at least 18.

Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Longevity / Anti-aging

Nad+ — reference

A central redox coenzyme, administered by IV infusion or injection in wellness settings on claims of energy and cellular repair.

Regulatory statusNot FDA-Approved
Published half-lifeMinutes in plasma (rapidly metabolized); IV infusion protocols exist because of this
Evidence levelLimited data
CategoryLongevity / Anti-aging

Regulatory status

Not FDA-Approved. Not FDA-approved for any of the uses it is marketed for. IV NAD+ is compounded and administered outside an approved indication.

Reported cautions

⚠ Worth knowing. Infusions are commonly reported to cause chest tightness, nausea and cramping when run quickly, which is why they are given slowly. The claimed benefits are not supported by controlled trials.

Pharmacokinetics

Published figures give an elimination half-life of Minutes in plasma (rapidly metabolized); IV infusion protocols exist because of this. Not a stable circulating molecule — 'half-life' is a less meaningful concept here than for a typical peptide.

This figure is tagged Limited data in our evidence system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is Nad+ FDA-approved?
Not FDA-Approved. Not FDA-approved for any of the uses it is marketed for. IV NAD+ is compounded and administered outside an approved indication.
What is the half-life of Nad+?
Published figures give Minutes in plasma (rapidly metabolized); IV infusion protocols exist because of this. Not a stable circulating molecule — 'half-life' is a less meaningful concept here than for a typical peptide.
How reliable is that half-life figure?
It is tagged “Limited data” in our system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only.
What cautions are associated with Nad+?
Infusions are commonly reported to cause chest tightness, nausea and cramping when run quickly, which is why they are given slowly. The claimed benefits are not supported by controlled trials.
Does Peptide Plug publish dosing for Nad+?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell Nad+?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

Related tools

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Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures