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Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Healing & Recovery

Ll-37 — reference

A human cathelicidin antimicrobial peptide with roles in innate immunity and wound healing.

Regulatory statusNot FDA-Approved
Published half-lifeShort — rapidly proteolyzed in vivo; not well characterized in humans
Evidence levelNot characterised
CategoryHealing & Recovery

Regulatory status

Not FDA-Approved. Not approved for therapeutic use. Naturally produced in the body; administering it exogenously is not a studied intervention.

Reported cautions

⚠ Worth knowing. Has both pro- and anti-inflammatory activity depending on context and concentration, and has been implicated in inflammatory skin conditions such as rosacea. Not a straightforwardly beneficial peptide.

Pharmacokinetics

Published figures give an elimination half-life of Short — rapidly proteolyzed in vivo; not well characterized in humans. Most data comes from in-vitro antimicrobial/immune studies, not systemic PK.

This figure is tagged Not characterised in our evidence system. No reliable human pharmacokinetic data was found for this compound. We publish that fact rather than a number borrowed from an unreliable source. Any estimated curve here would be fiction, and should be treated as such. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is Ll-37 FDA-approved?
Not FDA-Approved. Not approved for therapeutic use. Naturally produced in the body; administering it exogenously is not a studied intervention.
What is the half-life of Ll-37?
Published figures give Short — rapidly proteolyzed in vivo; not well characterized in humans. Most data comes from in-vitro antimicrobial/immune studies, not systemic PK.
How reliable is that half-life figure?
It is tagged “Not characterised” in our system. No reliable human pharmacokinetic data was found for this compound. We publish that fact rather than a number borrowed from an unreliable source. Any estimated curve here would be fiction, and should be treated as such.
What cautions are associated with Ll-37?
Has both pro- and anti-inflammatory activity depending on context and concentration, and has been implicated in inflammatory skin conditions such as rosacea. Not a straightforwardly beneficial peptide.
Does Peptide Plug publish dosing for Ll-37?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell Ll-37?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

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Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures