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Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Longevity / Anti-aging

Glutathione — reference

The body's principal intracellular antioxidant, sold as an oral supplement and given by injection or IV in wellness and skin-lightening settings.

Regulatory statusNot FDA-Approved
Published half-lifeMinutes (rapidly cleared/metabolized); poor and variable bioavailability by any route
Evidence levelLimited data
CategoryLongevity / Anti-aging

Regulatory status

Not FDA-Approved. Oral glutathione is sold as a dietary supplement. Injectable glutathione is not FDA-approved, and the FDA has specifically warned against compounded injectable glutathione marketed for skin lightening.

Reported cautions

⚠ Worth knowing. Oral bioavailability is poor, which is the usual argument for injecting it — but injectable products are unapproved and have been the subject of an explicit FDA safety communication.

Pharmacokinetics

Published figures give an elimination half-life of Minutes (rapidly cleared/metabolized); poor and variable bioavailability by any route. —

This figure is tagged Limited data in our evidence system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is Glutathione FDA-approved?
Not FDA-Approved. Oral glutathione is sold as a dietary supplement. Injectable glutathione is not FDA-approved, and the FDA has specifically warned against compounded injectable glutathione marketed for skin lightening.
What is the half-life of Glutathione?
Published figures give Minutes (rapidly cleared/metabolized); poor and variable bioavailability by any route. —
How reliable is that half-life figure?
It is tagged “Limited data” in our system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only.
What cautions are associated with Glutathione?
Oral bioavailability is poor, which is the usual argument for injecting it — but injectable products are unapproved and have been the subject of an explicit FDA safety communication.
Does Peptide Plug publish dosing for Glutathione?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell Glutathione?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

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Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures