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Peptide Plug is a research and organization tool intended for adults 18 years of age or older. By continuing, you confirm you are at least 18.

Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Skin / Healing

GHK-Cu — reference

Copper peptide — widely used topically in skincare; also used off-label as an injectable in some protocols.

Regulatory statusMixed Regulatory Status
Published half-lifeMinutes — rapidly metabolized once in circulation
Evidence levelLimited data
CategorySkin / Healing

Regulatory status

Mixed Regulatory Status. Topical use is a common cosmetic ingredient; injectable use is not FDA-approved.

Reported cautions

⚠ Worth knowing. Well studied topically, poorly studied by injection — the evidence base does not transfer between those routes. Delivers copper, so stacking multiple copper-containing products is the practical concern.

Pharmacokinetics

Published figures give an elimination half-life of Minutes — rapidly metabolized once in circulation. Topical use has essentially no meaningful systemic half-life to report.

This figure is tagged Limited data in our evidence system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is GHK-Cu FDA-approved?
Mixed Regulatory Status. Topical use is a common cosmetic ingredient; injectable use is not FDA-approved.
What is the half-life of GHK-Cu?
Published figures give Minutes — rapidly metabolized once in circulation. Topical use has essentially no meaningful systemic half-life to report.
How reliable is that half-life figure?
It is tagged “Limited data” in our system. The available data does not support a confident single figure, so this entry is flagged accordingly. Read any curve built from it as illustrative only.
What cautions are associated with GHK-Cu?
Well studied topically, poorly studied by injection — the evidence base does not transfer between those routes. Delivers copper, so stacking multiple copper-containing products is the practical concern.
Does Peptide Plug publish dosing for GHK-Cu?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell GHK-Cu?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

Related tools

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Estimated rise-and-fall curve between doses.
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Half-Life Data Table
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Pro Protocol Reference

The public research page intentionally does not publish dosing. Pro subscribers can open the separate Protocol Library for structured indication, frequency, duration, notes, and review-first Cycle Builder import when a matching reference is available.

View Protocol Reference
Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures · All compounds A–Z