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Peptide Plug is a research and organization tool intended for adults 18 years of age or older. By continuing, you confirm you are at least 18.

Reference only · Not medical advice · For adults 18+ · No dosing information is published here
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Longevity / Anti-aging

Foxo4-Dri — reference

A designed peptide that disrupts the FOXO4-p53 interaction, studied in mice as a senolytic to clear senescent cells.

Regulatory statusNot FDA-Approved
Published half-lifeNo published human PK data — research/preclinical only
Evidence levelNot characterised
CategoryLongevity / Anti-aging

Regulatory status

Not FDA-Approved. Never tested in humans. All published work is in mice.

Reported cautions

⚠ Worth knowing. Deliberately triggers apoptosis in senescent cells — a mechanism with obvious potential for off-target effects that mouse studies alone cannot characterise. Among the least justified compounds here for human use.

Pharmacokinetics

No published human PK data — research/preclinical only. Essentially no human safety or PK data exists for this compound at all.

This figure is tagged Not characterised in our evidence system. No reliable human pharmacokinetic data was found for this compound. We publish that fact rather than a number borrowed from an unreliable source. Any estimated curve here would be fiction, and should be treated as such. You can see the shape this implies between doses in the Half-Life Visualizer, and compare it against every other compound in the Half-Life Data Table. Our sourcing page explains what each tier means.

Remember that an estimated curve is a model built from a population figure, not a measurement of your blood. Individual clearance varies, and for depot injections the figure describes release from the injection site rather than the compound clearing. Half-life explained →

What Peptide Plug does and does not publish

This page carries regulatory status, general context and published pharmacokinetics. It carries no dose, frequency or cycle information — that is a deliberate editorial line, because dosing is a clinical decision rather than reference data. We also do not sell, supply, source or link to vendors for any compound.

Frequently asked

Is Foxo4-Dri FDA-approved?
Not FDA-Approved. Never tested in humans. All published work is in mice.
What is the half-life of Foxo4-Dri?
Published figures give No published human PK data — research/preclinical only. Essentially no human safety or PK data exists for this compound at all.
How reliable is that half-life figure?
It is tagged “Not characterised” in our system. No reliable human pharmacokinetic data was found for this compound. We publish that fact rather than a number borrowed from an unreliable source. Any estimated curve here would be fiction, and should be treated as such.
What cautions are associated with Foxo4-Dri?
Deliberately triggers apoptosis in senescent cells — a mechanism with obvious potential for off-target effects that mouse studies alone cannot characterise. Among the least justified compounds here for human use.
Does Peptide Plug publish dosing for Foxo4-Dri?
No. This library publishes regulatory status, general context and pharmacokinetics only. Dose, frequency and cycle information is deliberately absent from these public pages — those are clinical decisions, not reference data.
Does Peptide Plug sell Foxo4-Dri?
No. We do not sell, supply, source or link to vendors for any compound, and we have no affiliate arrangements with suppliers. Peptide Plug is a tracking and calculation tool.

Related tools

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Reference information, not medical advice. This page describes regulatory status and published pharmacokinetics. It does not tell you whether to use this compound, how much to use, how often, or whether it is safe for you. Peptide Plug does not sell, supply or source any compound. Those decisions belong to you and a licensed clinician.

Part of the Peptide Plug research library · How we source our figures